Protective role of vitamin E against valproic acid-induced cytogenotoxicity and hepatotoxicity in mice

Protective role of vitamin E against valproic acid-induced cytogenotoxicity and hepatotoxicity in mice

Valproic acid (VPA) is a widely used antiepileptic medication and has teratogenic effects in both animals and humans. The objective of the current study was to investigate the effects of vitamin E (Vit-E) on VPA induced cytogenotoxicity and hepatotoxicity in male albino mice (Mus musculus). Genotoxi...

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Bibliographic Details
Main Authors: Ehab M. Abdella, Sanaa R. Galaly, Hanaa M. Mohammed, Sally M. Khadrawy
Format: Article
Language:English
Published: SpringerOpen 2014-08-01
Series:Journal of Basic and Applied Zoology
Subjects:
Vitamin E
Valproic acid
Genotoxicity
Liver
Mice
Online Access:http://www.sciencedirect.com/science/article/pii/S2090989614000101

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