Mechanical and molecular parameters that influence the tendon differentiation potential of C3H10T1/2 cells in 2D- and 3D-culture systems

Mechanical and molecular parameters that influence the tendon differentiation potential of C3H10T1/2 cells in 2D- and 3D-culture systems

One of the main challenges relating to tendons is to understand the regulators of the tendon differentiation program. The optimum culture conditions that favor tendon cell differentiation have not been identified. Mesenchymal stem cells present the ability to differentiate into multiple lineages in...

Full description

Bibliographic Details
Main Authors: Ludovic Gaut, Marie-Ange Bonnin, Cédrine Blavet, Isabelle Cacciapuoti, Monika Orpel, Mathias Mericskay, Delphine Duprez
Format: Article
Language:English
Published: The Company of Biologists 2020-02-01
Series:Biology Open
Subjects:
mesenchymal stem cells
cell confluence
cell cultures
plastic substrate
silicone substrate
tendon differentiation
tgfβ2
scleraxis
tenomodulin
Online Access:http://bio.biologists.org/content/9/2/bio047928

Internet

http://bio.biologists.org/content/9/2/bio047928

Similar Items