Epitope Mapping of Metuximab on CD147 Using Phage Display and Molecular Docking

Epitope Mapping of Metuximab on CD147 Using Phage Display and Molecular Docking

Metuximab is the generic name of Licartin, a new drug for radioimmunotherapy of hepatocellular carcinoma. Although it is known to be a mouse monoclonal antibody against CD147, the complete epitope mediating the binding of metuximab to CD147 remains unknown. We panned the Ph.D.-12 phage display pepti...

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Bibliographic Details
Main Authors:	Bifang He, Canquan Mao, Beibei Ru, Hesong Han, Peng Zhou, Jian Huang
Format:	Article
Language:	English
Published:	Hindawi Limited 2013-01-01
Series:	Computational and Mathematical Methods in Medicine
Online Access:	http://dx.doi.org/10.1155/2013/983829

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