A fluorescence-based assay for measuring the redox potential of 5-lipoxygenase inhibitors.

The activities and side effects of 5-lipoxygenase (5-LO) inhibitors can be predicted by identifying their redox mechanisms. In this study, we developed a fluorescence-based method to measure the redox potential of 5-LO inhibitors and compared it to the conventional, absorbance-based method. After th...

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Bibliographic Details
Main Authors: Sangchul Lee, Youngsam Park, Junghwan Kim, Sung-Jun Han
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2014-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3912022?pdf=render