Defluorosilylation of fluoroarenes and fluoroalkanes

Transformation of strong C-F bonds into C-Si bonds is an extremely useful strategy for further derivatization of organic molecules. Here, the authors report a nickel-catalyzed strategy to convert aryl fluorides into sylylated arenes while defluorosilylation of alkyl fluorides is achieved under metal...

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Main Authors:	Benqiang Cui, Shichong Jia, Etsuko Tokunaga, Norio Shibata
Format:	Article
Language:	English
Published:	Nature Publishing Group 2018-10-01
Series:	Nature Communications
Online Access:	https://doi.org/10.1038/s41467-018-06830-w

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spelling	doaj-a0a3d223358c4f41bfbcfd034403093b2021-05-11T09:41:31ZengNature Publishing GroupNature Communications2041-17232018-10-01911810.1038/s41467-018-06830-wDefluorosilylation of fluoroarenes and fluoroalkanesBenqiang Cui0Shichong Jia1Etsuko Tokunaga2Norio Shibata3Department of Nanopharmaceutical Sciences and Department of Life Science and Applied Chemistry, Nagoya Institute of Technology, GokisoDepartment of Nanopharmaceutical Sciences and Department of Life Science and Applied Chemistry, Nagoya Institute of Technology, GokisoDepartment of Nanopharmaceutical Sciences and Department of Life Science and Applied Chemistry, Nagoya Institute of Technology, GokisoDepartment of Nanopharmaceutical Sciences and Department of Life Science and Applied Chemistry, Nagoya Institute of Technology, GokisoTransformation of strong C-F bonds into C-Si bonds is an extremely useful strategy for further derivatization of organic molecules. Here, the authors report a nickel-catalyzed strategy to convert aryl fluorides into sylylated arenes while defluorosilylation of alkyl fluorides is achieved under metal-free conditions.https://doi.org/10.1038/s41467-018-06830-w
collection	DOAJ
language	English
format	Article
sources	DOAJ
author	Benqiang Cui Shichong Jia Etsuko Tokunaga Norio Shibata
spellingShingle	Benqiang Cui Shichong Jia Etsuko Tokunaga Norio Shibata Defluorosilylation of fluoroarenes and fluoroalkanes Nature Communications
author_facet	Benqiang Cui Shichong Jia Etsuko Tokunaga Norio Shibata
author_sort	Benqiang Cui
title	Defluorosilylation of fluoroarenes and fluoroalkanes
title_short	Defluorosilylation of fluoroarenes and fluoroalkanes
title_full	Defluorosilylation of fluoroarenes and fluoroalkanes
title_fullStr	Defluorosilylation of fluoroarenes and fluoroalkanes
title_full_unstemmed	Defluorosilylation of fluoroarenes and fluoroalkanes
title_sort	defluorosilylation of fluoroarenes and fluoroalkanes
publisher	Nature Publishing Group
series	Nature Communications
issn	2041-1723
publishDate	2018-10-01
description	Transformation of strong C-F bonds into C-Si bonds is an extremely useful strategy for further derivatization of organic molecules. Here, the authors report a nickel-catalyzed strategy to convert aryl fluorides into sylylated arenes while defluorosilylation of alkyl fluorides is achieved under metal-free conditions.
url	https://doi.org/10.1038/s41467-018-06830-w
work_keys_str_mv	AT benqiangcui defluorosilylationoffluoroarenesandfluoroalkanes AT shichongjia defluorosilylationoffluoroarenesandfluoroalkanes AT etsukotokunaga defluorosilylationoffluoroarenesandfluoroalkanes AT norioshibata defluorosilylationoffluoroarenesandfluoroalkanes
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Defluorosilylation of fluoroarenes and fluoroalkanes

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