Enhanced analgesic cholinergic tone in the spinal cord in a mouse model of neuropathic pain

Enhanced analgesic cholinergic tone in the spinal cord in a mouse model of neuropathic pain

Endogenous acetylcholine (ACh) is an important modulator of nociceptive sensory processing in the spinal cord. An increased level of spinal ACh induces analgesia both in humans and rodents while interfering with cholinergic signaling is allodynic, demonstrating that a basal tone of spinal ACh modula...

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Bibliographic Details
Main Authors: Dhanasak Dhanasobhon, Maria-Carmen Medrano, Léa J. Becker, Yunuen Moreno-Lopez, Sehrazat Kavraal, Charlotte Bichara, Rémy Schlichter, Perrine Inquimbert, Ipek Yalcin, Matilde Cordero-Erausquin
Format: Article
Language:English
Published: Elsevier 2021-07-01
Series:Neurobiology of Disease
Online Access:http://www.sciencedirect.com/science/article/pii/S0969996121001121

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http://www.sciencedirect.com/science/article/pii/S0969996121001121

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