Erythrophagocytosis by blasts in a case of de novo acute monoblastic leukemia with rare but characteristic t(8;16)

Erythrophagocytosis by blasts in a case of de novo acute monoblastic leukemia with rare but characteristic t(8;16)

Erythrophagocytosis by leukemic blasts is a rare phenomenon. We report a case of a female diagnosed with acute monoblastic leukemia with leukemic blasts that were CD34 and CD117 negative, showing erythrophagocytosis, vacoulations, and a rare t(8;16) on bone marrow karyotype which is associated with...

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Main Authors: A Gupta, G K Reddy, M Goyal, M R Kasaragadda
Format: Article
Language:English
Published: Wolters Kluwer Medknow Publications 2017-01-01
Series:Journal of Postgraduate Medicine
Subjects:
Acute monoblastic leukemia
erythrophagocytosis by blasts
t(8;16)
Online Access:http://www.jpgmonline.com/article.asp?issn=0022-3859;year=2017;volume=63;issue=3;spage=194;epage=196;aulast=Gupta
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spelling doaj-a09fbeb92a4d442c83d9ac61373555172020-11-25T01:38:29ZengWolters Kluwer Medknow PublicationsJournal of Postgraduate Medicine0022-38590972-28232017-01-0163319419610.4103/0022-3859.201413Erythrophagocytosis by blasts in a case of de novo acute monoblastic leukemia with rare but characteristic t(8;16)A GuptaG K ReddyM GoyalM R KasaragaddaErythrophagocytosis by leukemic blasts is a rare phenomenon. We report a case of a female diagnosed with acute monoblastic leukemia with leukemic blasts that were CD34 and CD117 negative, showing erythrophagocytosis, vacoulations, and a rare t(8;16) on bone marrow karyotype which is associated with a poor prognosis despite intensive chemotherapy. Meticulous bone marrow examination in such a scenario may point towards the presence of t(8;16) and help clinicians take a well-informed clinical decision.http://www.jpgmonline.com/article.asp?issn=0022-3859;year=2017;volume=63;issue=3;spage=194;epage=196;aulast=GuptaAcute monoblastic leukemiaerythrophagocytosis by blastst(8;16)
collection DOAJ
language English
format Article
sources DOAJ
author A Gupta
G K Reddy
M Goyal
M R Kasaragadda
spellingShingle A Gupta
G K Reddy
M Goyal
M R Kasaragadda
Erythrophagocytosis by blasts in a case of de novo acute monoblastic leukemia with rare but characteristic t(8;16)
Journal of Postgraduate Medicine
Acute monoblastic leukemia
erythrophagocytosis by blasts
t(8;16)
author_facet A Gupta
G K Reddy
M Goyal
M R Kasaragadda
author_sort A Gupta
title Erythrophagocytosis by blasts in a case of de novo acute monoblastic leukemia with rare but characteristic t(8;16)
title_short Erythrophagocytosis by blasts in a case of de novo acute monoblastic leukemia with rare but characteristic t(8;16)
title_full Erythrophagocytosis by blasts in a case of de novo acute monoblastic leukemia with rare but characteristic t(8;16)
title_fullStr Erythrophagocytosis by blasts in a case of de novo acute monoblastic leukemia with rare but characteristic t(8;16)
title_full_unstemmed Erythrophagocytosis by blasts in a case of de novo acute monoblastic leukemia with rare but characteristic t(8;16)
title_sort erythrophagocytosis by blasts in a case of de novo acute monoblastic leukemia with rare but characteristic t(8;16)
publisher Wolters Kluwer Medknow Publications
series Journal of Postgraduate Medicine
issn 0022-3859
0972-2823
publishDate 2017-01-01
description Erythrophagocytosis by leukemic blasts is a rare phenomenon. We report a case of a female diagnosed with acute monoblastic leukemia with leukemic blasts that were CD34 and CD117 negative, showing erythrophagocytosis, vacoulations, and a rare t(8;16) on bone marrow karyotype which is associated with a poor prognosis despite intensive chemotherapy. Meticulous bone marrow examination in such a scenario may point towards the presence of t(8;16) and help clinicians take a well-informed clinical decision.
topic Acute monoblastic leukemia
erythrophagocytosis by blasts
t(8;16)
url http://www.jpgmonline.com/article.asp?issn=0022-3859;year=2017;volume=63;issue=3;spage=194;epage=196;aulast=Gupta
work_keys_str_mv AT agupta erythrophagocytosisbyblastsinacaseofdenovoacutemonoblasticleukemiawithrarebutcharacteristict816
AT gkreddy erythrophagocytosisbyblastsinacaseofdenovoacutemonoblasticleukemiawithrarebutcharacteristict816
AT mgoyal erythrophagocytosisbyblastsinacaseofdenovoacutemonoblasticleukemiawithrarebutcharacteristict816
AT mrkasaragadda erythrophagocytosisbyblastsinacaseofdenovoacutemonoblasticleukemiawithrarebutcharacteristict816
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