Interleukin-17A promotes MUC5AC expression and goblet cell hyperplasia in nasal polyps via the Act1-mediated pathway.

BACKGROUND: Recent studies demonstrated that nasal polyps (NP) patients in China and other Asian regions possessed distinct Th17-dominant inflammation and enhanced tissue remodeling. However, the mechanism underlying these observations is not fully understood. This study sought to evaluate the assoc...

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Bibliographic Details
Main Authors: Wentong Xia, Jing Bai, Xingmei Wu, Yi Wei, Shaoyan Feng, Lei Li, Jia Zhang, Guanxia Xiong, Yunping Fan, Jianbo Shi, Huabin Li
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2014-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4043856?pdf=render