MicroRNA-449a Inhibits Proliferation and Induces Apoptosis by Directly Repressing E2F3 in Gastric Cancer

MicroRNA-449a Inhibits Proliferation and Induces Apoptosis by Directly Repressing E2F3 in Gastric Cancer

Background: MicroRNA-449a is a tumor suppressor that is down-regulated in multiple tumors types. However, the role of miR-449a in gastric cancer (GC) remains largely unknown. Methods: MiR-449a expression was up-regulated using miR-449a mimics, and the role of miR-449a in GC was assessed using cell v...

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Bibliographic Details
Main Authors: Xiaoping Li, Hong Li, Rui Zhang, Jing Liu, Jun Liu
Format: Article
Language:English
Published: Cell Physiol Biochem Press GmbH & Co KG 2015-03-01
Series:Cellular Physiology and Biochemistry
Subjects:
Proliferation
Apoptosis
E2F3
Gastric cancer
MiR-449a
Online Access:http://www.karger.com/Article/FullText/374010

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