Impact of Na+/Ca2+ Exchangers on Therapy Resistance of Ovary Carcinoma Cells

Impact of Na+/Ca2+ Exchangers on Therapy Resistance of Ovary Carcinoma Cells

Background/Aims: According to previous observations, enhanced store-operated Ca2+-entry (SOCE) accomplished by the pore forming ion channel unit Orai1 and its regulator STIM1 contribute to therapy resistance of ovary carcinoma cells. Ca2+ signaling is further shaped by Ca2+ extrusion through K+-inde...

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Bibliographic Details
Main Authors: Lisann Pelzl, Zohreh Hosseinzadeh, Kousi Alzoubi, Tamer Al-Maghout, Sebastian Schmidt, Christos Stournaras, Florian Lang
Format: Article
Language:English
Published: Cell Physiol Biochem Press GmbH & Co KG 2015-11-01
Series:Cellular Physiology and Biochemistry
Subjects:
NCX3
NCKX4
NCKX5
NCKX6
Cisplatin
Apoptosis
Online Access:http://www.karger.com/Article/FullText/438547

Internet

http://www.karger.com/Article/FullText/438547

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