Cldn-7 deficiency promotes experimental colitis and associated carcinogenesis by regulating intestinal epithelial integrity

Cldn-7 deficiency promotes experimental colitis and associated carcinogenesis by regulating intestinal epithelial integrity

Intestinal epithelial barrier protects intestine from infection and injury, while chronic inflammation is a trigger for tumorigenesis. As a member of tight junctions (TJs) family, Claudin-7 (Cldn-7) is dedicated to maintaining cell polarity and TJs barrier integrity, and closely related to the devel...

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Bibliographic Details
Main Authors:	Kun Wang, Yuhan Ding, Chang Xu, Mengdi Hao, Huimin Li, Lei Ding
Format:	Article
Language:	English
Published:	Taylor & Francis Group 2021-01-01
Series:	OncoImmunology
Subjects:	cldn-7 inflammation colitis-associated cancer intestinal epithelial homeostasis
Online Access:	http://dx.doi.org/10.1080/2162402X.2021.1923910

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