Developing a Color-Based Molecular Sensing Device: DETECHIP®
DETECHIP® is a detection system made of various sensors that has been shown to detect and discriminate between small molecules of interest, including various illicit drugs for and over- the-counter medications, explosives, pesticides and food spoilage metabolites. DETECHIP® employs an array of senso...
Main Authors: | , |
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Format: | Article |
Language: | English |
Published: |
IFSA Publishing, S.L.
2014-12-01
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Series: | Sensors & Transducers |
Subjects: | |
Online Access: | http://www.sensorsportal.com/HTML/DIGEST/december_2014/Vol_183/P_2538.pdf |
Summary: | DETECHIP® is a detection system made of various sensors that has been shown to detect and discriminate between small molecules of interest, including various illicit drugs for and over- the-counter medications, explosives, pesticides and food spoilage metabolites. DETECHIP® employs an array of sensors from which an analyte is tested and based on changes in color; a code specific to the analyte is developed. DETECHIP® offers possibilities for a simple, sensitive, selective, and affordable alternative to costly immunoassays. Results from NMR, UV-VIS and fluorimetry studies suggest that the color and fluorescence changes are a result of intermolecular interaction between the analytes and sensors ranging from non-covalent covalent bonding of supramolecular structure to proton exchange between the analyte and sensor molecules. Current efforts are focused on miniaturization of DETECHIP® to the micro and nanoscale.
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ISSN: | 2306-8515 1726-5479 |