Developing a Color-Based Molecular Sensing Device: DETECHIP®

DETECHIP® is a detection system made of various sensors that has been shown to detect and discriminate between small molecules of interest, including various illicit drugs for and over- the-counter medications, explosives, pesticides and food spoilage metabolites. DETECHIP® employs an array of senso...

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Bibliographic Details
Main Authors: Macduff O. OKUOM, Andrea E. HOLMES
Format: Article
Language:English
Published: IFSA Publishing, S.L. 2014-12-01
Series:Sensors & Transducers
Subjects:
Online Access:http://www.sensorsportal.com/HTML/DIGEST/december_2014/Vol_183/P_2538.pdf
Description
Summary:DETECHIP® is a detection system made of various sensors that has been shown to detect and discriminate between small molecules of interest, including various illicit drugs for and over- the-counter medications, explosives, pesticides and food spoilage metabolites. DETECHIP® employs an array of sensors from which an analyte is tested and based on changes in color; a code specific to the analyte is developed. DETECHIP® offers possibilities for a simple, sensitive, selective, and affordable alternative to costly immunoassays. Results from NMR, UV-VIS and fluorimetry studies suggest that the color and fluorescence changes are a result of intermolecular interaction between the analytes and sensors ranging from non-covalent covalent bonding of supramolecular structure to proton exchange between the analyte and sensor molecules. Current efforts are focused on miniaturization of DETECHIP® to the micro and nanoscale.
ISSN:2306-8515
1726-5479