A chromosome-scale assembly of the sorghum genome using nanopore sequencing and optical mapping

Assembly of large, repeat-rich eukaryotic genomes remains challenging. Here, the authors use BioNano Genomics DLS optical mapping and single-molecule nanopore sequencing to generate a chromosome-scale assembly of a new Sorghum bicolor accession and identify variation compared to the publicly availab...

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Main Authors:	Stéphane Deschamps, Yun Zhang, Victor Llaca, Liang Ye, Abhijit Sanyal, Matthew King, Gregory May, Haining Lin
Format:	Article
Language:	English
Published:	Nature Publishing Group 2018-11-01
Series:	Nature Communications
Online Access:	https://doi.org/10.1038/s41467-018-07271-1

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spelling	doaj-a094b1e394dd4d97aefd9a454c9da9382021-05-11T09:25:51ZengNature Publishing GroupNature Communications2041-17232018-11-019111010.1038/s41467-018-07271-1A chromosome-scale assembly of the sorghum genome using nanopore sequencing and optical mappingStéphane Deschamps0Yun Zhang1Victor Llaca2Liang Ye3Abhijit Sanyal4Matthew King5Gregory May6Haining Lin7Corteva Agriscience™, Agriculture Division of DowDuPont™Corteva Agriscience™, Agriculture Division of DowDuPont™Corteva Agriscience™, Agriculture Division of DowDuPont™Corteva Agriscience™, Agriculture Division of DowDuPont™Corteva Agriscience™, Agriculture Division of DowDuPont™Corteva Agriscience™, Agriculture Division of DowDuPont™Corteva Agriscience™, Agriculture Division of DowDuPont™Corteva Agriscience™, Agriculture Division of DowDuPont™Assembly of large, repeat-rich eukaryotic genomes remains challenging. Here, the authors use BioNano Genomics DLS optical mapping and single-molecule nanopore sequencing to generate a chromosome-scale assembly of a new Sorghum bicolor accession and identify variation compared to the publicly available S. bicolor genome.https://doi.org/10.1038/s41467-018-07271-1
collection	DOAJ
language	English
format	Article
sources	DOAJ
author	Stéphane Deschamps Yun Zhang Victor Llaca Liang Ye Abhijit Sanyal Matthew King Gregory May Haining Lin
spellingShingle	Stéphane Deschamps Yun Zhang Victor Llaca Liang Ye Abhijit Sanyal Matthew King Gregory May Haining Lin A chromosome-scale assembly of the sorghum genome using nanopore sequencing and optical mapping Nature Communications
author_facet	Stéphane Deschamps Yun Zhang Victor Llaca Liang Ye Abhijit Sanyal Matthew King Gregory May Haining Lin
author_sort	Stéphane Deschamps
title	A chromosome-scale assembly of the sorghum genome using nanopore sequencing and optical mapping
title_short	A chromosome-scale assembly of the sorghum genome using nanopore sequencing and optical mapping
title_full	A chromosome-scale assembly of the sorghum genome using nanopore sequencing and optical mapping
title_fullStr	A chromosome-scale assembly of the sorghum genome using nanopore sequencing and optical mapping
title_full_unstemmed	A chromosome-scale assembly of the sorghum genome using nanopore sequencing and optical mapping
title_sort	chromosome-scale assembly of the sorghum genome using nanopore sequencing and optical mapping
publisher	Nature Publishing Group
series	Nature Communications
issn	2041-1723
publishDate	2018-11-01
description	Assembly of large, repeat-rich eukaryotic genomes remains challenging. Here, the authors use BioNano Genomics DLS optical mapping and single-molecule nanopore sequencing to generate a chromosome-scale assembly of a new Sorghum bicolor accession and identify variation compared to the publicly available S. bicolor genome.
url	https://doi.org/10.1038/s41467-018-07271-1
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A chromosome-scale assembly of the sorghum genome using nanopore sequencing and optical mapping

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