Array-Based Comparative Genomic Hybridization Identifies Localized DNA Amplifications and Homozygous Deletions in Pancreatic Cancer

Array-Based Comparative Genomic Hybridization Identifies Localized DNA Amplifications and Homozygous Deletions in Pancreatic Cancer

Pancreatic cancer, the fourth leading cause of cancer death in the United States, is frequently associated with the amplification and deletion of specific oncogenes and tumor-suppressor genes (TSGs), respectively. To identify such novel alterations and to discover the underlying genes, we performed...

Full description

Bibliographic Details
Main Authors: Murali D. Bashyam, Ryan Bair, Young H. Kim, Pei Wang, Tina Hernandez-Boussard, Collins A. Karikari, Robert Tibshirani, Anirban Maitra, Jonathan R. Pollack
Format: Article
Language:English
Published: Elsevier 2005-06-01
Series:Neoplasia: An International Journal for Oncology Research
Subjects:
Pancreatic cancer
array CGH
comparative genomic hybridization
expression profiling
DNA amplification
Online Access:http://www.sciencedirect.com/science/article/pii/S1476558605800764

Internet

http://www.sciencedirect.com/science/article/pii/S1476558605800764

Similar Items