Platinum-containing compound platinum pyrithione suppresses ovarian tumor proliferation through proteasome inhibition

Platinum-containing compound platinum pyrithione suppresses ovarian tumor proliferation through proteasome inhibition

Abstract Background Ovarian carcinoma is one of the most aggressive gynecological malignant neoplasms and makes up 25–30% of all cancer cases of the female genital tract. Currently, resistance to traditional chemotherapy is a great challenge for patients with Epithelial ovarian cancer (EOC). Therefo...

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Bibliographic Details
Main Authors: Hongbiao Huang, Ni Liu, Yuning Liao, Ningning Liu, Jianyu Cai, Xiaohong Xia, Zhiqiang Guo, Yanling Li, Qirong Wen, Qi Yin, Yan Liu, Qingxia Wu, Dhivya Rajakumar, Xiujie Sheng, Jinbao Liu
Format: Article
Language:English
Published: BMC 2017-06-01
Series:Journal of Experimental & Clinical Cancer Research
Subjects:
PtPT
Proteasome
Deubiquitinase
Epithelial ovarian cancer
Proliferation
Online Access:http://link.springer.com/article/10.1186/s13046-017-0547-8

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http://link.springer.com/article/10.1186/s13046-017-0547-8

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