Oligodendrocytes Support Neuronal Glutamatergic Transmission via Expression of Glutamine Synthetase

Summary: Glutamate has been implicated in a wide range of brain pathologies and is thought to be metabolized via the astrocyte-specific enzyme glutamine synthetase (GS). We show here that oligodendrocytes, the myelinating glia of the central nervous system, also express high levels of GS in caudal r...

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Bibliographic Details
Main Authors: Wendy Xin, Yevgeniya A. Mironova, Hui Shen, Rosa A.M. Marino, Ari Waisman, Wouter H. Lamers, Dwight E. Bergles, Antonello Bonci
Format: Article
Language:English
Published: Elsevier 2019-05-01
Series:Cell Reports
Online Access:http://www.sciencedirect.com/science/article/pii/S2211124719305741