Human natural killer cell maturation defect supports in vivo CD56(bright) to CD56(dim) lineage development.

Human natural killer cell maturation defect supports in vivo CD56(bright) to CD56(dim) lineage development.

Two populations of human natural killer (NK) cells can be identified in peripheral blood. The majority are CD3(-)CD56(dim) cells while the minority exhibits a CD3(-)CD56(bright) phenotype. In vitro evidence indicates that CD56(bright) cells are precursors of CD56(dim) cells, but in vivo evidence is...

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Bibliographic Details
Main Authors: Carolina Inés Domaica, Mercedes Beatriz Fuertes, Ignacio Uriarte, María Victoria Girart, Jessica Sardañons, Dorina Ileana Comas, Daniela Di Giovanni, María Isabel Gaillard, Liliana Bezrodnik, Norberto Walter Zwirner
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2012-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3519873?pdf=render

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http://europepmc.org/articles/PMC3519873?pdf=render

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