Apalutamide in the treatment of castrate-resistant prostate cancer: evidence from clinical trials
Apalutamide (ARN-509) is a second-generation androgen receptor (AR) antagonist that was developed to inhibit AR-mediated prostate cancer cell proliferation. Following the initial promising clinical efficacy results in phase I and II clinical trials of patients with metastatic castrate-resistant pros...
Main Authors: | , |
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Format: | Article |
Language: | English |
Published: |
SAGE Publishing
2018-12-01
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Series: | Therapeutic Advances in Urology |
Online Access: | https://doi.org/10.1177/1756287218811450 |