Apalutamide in the treatment of castrate-resistant prostate cancer: evidence from clinical trials

Apalutamide (ARN-509) is a second-generation androgen receptor (AR) antagonist that was developed to inhibit AR-mediated prostate cancer cell proliferation. Following the initial promising clinical efficacy results in phase I and II clinical trials of patients with metastatic castrate-resistant pros...

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Bibliographic Details
Main Authors: Vadim S. Koshkin, Eric J. Small
Format: Article
Language:English
Published: SAGE Publishing 2018-12-01
Series:Therapeutic Advances in Urology
Online Access:https://doi.org/10.1177/1756287218811450