Leptin enhances availability of apoptotic cell-derived self-antigen in systemic lupus erythematosus.

Leptin enhances availability of apoptotic cell-derived self-antigen in systemic lupus erythematosus.

In systemic lupus erythematosus (SLE), the availability of self-antigen promotes and fuels self-reactive immune responses. Apoptotic cells represent a major source of self-antigens, and an impairment of the removal of apoptotic material containing self-antigen can contribute to the development of au...

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Bibliographic Details
Main Authors: Gil Amarilyo, Noriko Iikuni, Aijing Liu, Giuseppe Matarese, Antonio La Cava
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2014-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4234630?pdf=render

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