Selective proliferative response of microglia to alternative polarization signals

Selective proliferative response of microglia to alternative polarization signals

Abstract Background Microglia are resident myeloid cells of the central nervous system (CNS) that are maintained by self-renewal and actively participate in tissue homeostasis and immune defense. Under the influence of endogenous or pathological signals, microglia undertake biochemical transformatio...

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Bibliographic Details
Main Authors: Giovanna Pepe, Marcella De Maglie, Lucia Minoli, Alessandro Villa, Adriana Maggi, Elisabetta Vegeto
Format: Article
Language:English
Published: BMC 2017-12-01
Series:Journal of Neuroinflammation
Subjects:
Interleukin-4
Microglia
Proliferation
Estrogen
Online Access:http://link.springer.com/article/10.1186/s12974-017-1011-6

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