A new rat model of treatment-naive quiescent choroidal neovascularization induced by human VEGF165 overexpression

A new rat model of treatment-naive quiescent choroidal neovascularization induced by human VEGF165 overexpression

Vascular endothelial growth factor (VEGF) is a crucial stimulator for choroidal neovascularization (CNV). Our aim was to develop a reproducible and valid treatment-naive quiescent CNV (i.e. without signs of exudation and with normal visual acuity) rat model by subretinal injection of an adeno-associ...

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Bibliographic Details
Main Authors: Shan Liu, Antje K. Biesemeier, Alexander V. Tschulakow, Harsh V. Thakkar, Sylvie Julien-Schraermeyer, Ulrich Schraermeyer
Format: Article
Language:English
Published: The Company of Biologists 2020-06-01
Series:Biology Open
Subjects:
choroidal neovascularization (cnv)
vascular endothelial growth factor (vegf)
electron microscopy (em)
bevacizumab
angiogenesis
age-related macular degeneration (amd)
Online Access:http://bio.biologists.org/content/9/6/bio048736

Internet

http://bio.biologists.org/content/9/6/bio048736

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