Identification of an acute functional cross-talk between amyloid-β and glucocorticoid receptors at hippocampal excitatory synapses

Identification of an acute functional cross-talk between amyloid-β and glucocorticoid receptors at hippocampal excitatory synapses

Amyloid-β is a peptide released by synapses in physiological conditions and its pathological accumulation in brain structures necessary for memory processing represents a key toxic hallmark underlying Alzheimer's disease. The oligomeric form of Amyloid-β (Aβο) is now believed to represent the m...

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Bibliographic Details
Main Authors: Scherazad Kootar, Marie-Lise Frandemiche, Gihen Dhib, Xavier Mouska, Thomas Lorivel, Gwenola Poupon-Silvestre, Hazel Hunt, François Tronche, Ingrid Bethus, Jacques Barik, Hélène Marie
Format: Article
Language:English
Published: Elsevier 2018-10-01
Series:Neurobiology of Disease
Subjects:
Amyloid-β
Glucocorticoid receptor
Synapse function
Hippocampus
Stress
Alzheimer's disease
Online Access:http://www.sciencedirect.com/science/article/pii/S0969996118302109

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http://www.sciencedirect.com/science/article/pii/S0969996118302109

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