tRNA Queuosine Modification Enzyme Modulates the Growth and Microbiome Recruitment to Breast Tumors

tRNA Queuosine Modification Enzyme Modulates the Growth and Microbiome Recruitment to Breast Tumors

Background: Transfer RNA (tRNA) queuosine (Q)-modifications occur specifically in 4 cellular tRNAs at the wobble anticodon position. tRNA Q-modification in human cells depends on the gut microbiome because the microbiome product queuine is required for its installation by the enzyme Q tRNA ribosyltr...

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Bibliographic Details
Main Authors: Jilei Zhang, Rong Lu, Yongguo Zhang, Żaneta Matuszek, Wen Zhang, Yinglin Xia, Tao Pan, Jun Sun
Format: Article
Language:English
Published: MDPI AG 2020-03-01
Series:Cancers
Subjects:
breast cancer
breast microbiome
gut microbiome
inflammation
micronutrient
queuosine
queuine, qtrt1
permeability
proliferation
tight junctions
Online Access:https://www.mdpi.com/2072-6694/12/3/628

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