Association between CTL precursor frequency to HLA-C mismatches and HLA-C antigen cell surface expression

Association between CTL precursor frequency to HLA-C mismatches and HLA-C antigen cell surface expression

Previous studies showed the relevance of the cytotoxic T cell precursor frequency assay (CTLp) for prediction of the outcome of HLA mismatched hematopoietic cell transplantation (HCT). Recently it has been shown that HLA-C cell surface expression is correlated with virus specific cytotoxic T cell re...

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Bibliographic Details
Main Authors: Moshe eIsraeli, Dave L. Roelen, Mary eCarrington, Effie Wang Petersdorf, Frans HJ Claas, Geert W Haasnoot, Machteld eOudshoorn
Format: Article
Language:English
Published: Frontiers Media S.A. 2014-10-01
Series:Frontiers in Immunology
Subjects:
alloreactivity
HLA-C
cell surface expression
cytotoxic T cell precursor frequency
CTLp assay
Online Access:http://journal.frontiersin.org/Journal/10.3389/fimmu.2014.00547/full

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