Modeling circadian variability of core-clock and clock-controlled genes in four tissues of the rat.

Circadian clocks, present in almost all cells of the body, are entrained to rhythmic changes in the environment (e.g. light/dark cycles). Genes responsible for this timekeeping are named core-clock genes, which through transcriptional feedback interactions mediated by transcription factor binding to...

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Bibliographic Details
Main Authors: Panteleimon D Mavroudis, Debra C DuBois, Richard R Almon, William J Jusko
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2018-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC5997360?pdf=render