RocSampler: regularizing overlapping protein complexes in protein-protein interaction networks

RocSampler: regularizing overlapping protein complexes in protein-protein interaction networks

Abstract Background In recent years, protein-protein interaction (PPI) networks have been well recognized as important resources to elucidate various biological processes and cellular mechanisms. In this paper, we address the problem of predicting protein complexes from a PPI network. This problem h...

Full description

Bibliographic Details
Main Authors: Osamu Maruyama, Yuki Kuwahara
Format: Article
Language:English
Published: BMC 2017-12-01
Series:BMC Bioinformatics
Subjects:
Protein-protein interaction
Protein complex
Markov chain Monte Carlo
RocSampler
Regularization term
Online Access:http://link.springer.com/article/10.1186/s12859-017-1920-5

Internet

http://link.springer.com/article/10.1186/s12859-017-1920-5

Similar Items