Harnessing the Power of Eph/ephrin Biosemiotics for Theranostic Applications

Harnessing the Power of Eph/ephrin Biosemiotics for Theranostic Applications

Comprehensive basic biological knowledge of the Eph/ephrin system in the physiologic setting is needed to facilitate an understanding of its role and the effects of pathological processes on its activity, thereby paving the way for development of prospective therapeutic targets. To this end, this re...

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Main Authors: Robert M. Hughes, Jitka A.I. Virag
Format: Article
Language:English
Published: MDPI AG 2020-06-01
Series:Pharmaceuticals
Subjects:
Eph/ephrin
receptor tyrosine kinase
therapeutic target
smart drug
nanoparticles
liposomes
Online Access:https://www.mdpi.com/1424-8247/13/6/112
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spelling doaj-a020badab1314fdaa47496674f2d22222020-11-25T03:51:56ZengMDPI AGPharmaceuticals1424-82472020-06-011311211210.3390/ph13060112Harnessing the Power of Eph/ephrin Biosemiotics for Theranostic ApplicationsRobert M. Hughes0Jitka A.I. Virag1Department of Chemistry, East Carolina University, Science and Technology Building, SZ564, East 5th St, Greenville, NC 27858, USADepartment of Physiology, Brody School of Medicine, East Carolina University, Warren Life Sciences Building, LSB239, 600 Moye Blvd, Greenville, NC 27834, USAComprehensive basic biological knowledge of the Eph/ephrin system in the physiologic setting is needed to facilitate an understanding of its role and the effects of pathological processes on its activity, thereby paving the way for development of prospective therapeutic targets. To this end, this review briefly addresses what is currently known and being investigated in order to highlight the gaps and possible avenues for further investigation to capitalize on their diverse potential.https://www.mdpi.com/1424-8247/13/6/112Eph/ephrinreceptor tyrosine kinasetherapeutic targetsmart drugnanoparticlesliposomes
collection DOAJ
language English
format Article
sources DOAJ
author Robert M. Hughes
Jitka A.I. Virag
spellingShingle Robert M. Hughes
Jitka A.I. Virag
Harnessing the Power of Eph/ephrin Biosemiotics for Theranostic Applications
Pharmaceuticals
Eph/ephrin
receptor tyrosine kinase
therapeutic target
smart drug
nanoparticles
liposomes
author_facet Robert M. Hughes
Jitka A.I. Virag
author_sort Robert M. Hughes
title Harnessing the Power of Eph/ephrin Biosemiotics for Theranostic Applications
title_short Harnessing the Power of Eph/ephrin Biosemiotics for Theranostic Applications
title_full Harnessing the Power of Eph/ephrin Biosemiotics for Theranostic Applications
title_fullStr Harnessing the Power of Eph/ephrin Biosemiotics for Theranostic Applications
title_full_unstemmed Harnessing the Power of Eph/ephrin Biosemiotics for Theranostic Applications
title_sort harnessing the power of eph/ephrin biosemiotics for theranostic applications
publisher MDPI AG
series Pharmaceuticals
issn 1424-8247
publishDate 2020-06-01
description Comprehensive basic biological knowledge of the Eph/ephrin system in the physiologic setting is needed to facilitate an understanding of its role and the effects of pathological processes on its activity, thereby paving the way for development of prospective therapeutic targets. To this end, this review briefly addresses what is currently known and being investigated in order to highlight the gaps and possible avenues for further investigation to capitalize on their diverse potential.
topic Eph/ephrin
receptor tyrosine kinase
therapeutic target
smart drug
nanoparticles
liposomes
url https://www.mdpi.com/1424-8247/13/6/112
work_keys_str_mv AT robertmhughes harnessingthepowerofephephrinbiosemioticsfortheranosticapplications
AT jitkaaivirag harnessingthepowerofephephrinbiosemioticsfortheranosticapplications
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