Lentiviral vectors encoding tetracycline-dependent repressors and transactivators for reversible knockdown of gene expression: a comparative study

<p>Abstract</p> <p>Background</p> <p>RNA interference (RNAi)-mediated by the expression of short hairpin RNAs (shRNAs) has emerged as a powerful experimental tool for reverse genetic studies in mammalian cells. A number of recent reports have described approaches allowi...

Full description

Bibliographic Details
Main Authors: Bialkowska Agnieszka, Kutner Robert, Zhang Xian-Yang, Diehl William, Pluta Krzysztof, Reiser Jakob
Format: Article
Language:English
Published: BMC 2007-07-01
Series:BMC Biotechnology
Online Access:http://www.biomedcentral.com/1472-6750/7/41