Chelerythrine Attenuates Renal Ischemia/Reperfusion-induced Myocardial Injury by Activating CSE/H2S via PKC/NF-κB Pathway in Diabetic Rats

Chelerythrine Attenuates Renal Ischemia/Reperfusion-induced Myocardial Injury by Activating CSE/H2S via PKC/NF-κB Pathway in Diabetic Rats

Background/Aims: Chelerythrine (CHE), a benzophenanthridine alkaloid, is a potent, selective, and cell-permeable protein kinase C (PKC) inhibitor. The purpose of the present study was to evaluate the effect of CHE on myocardial recovery after renal ischemia/reperfusion (I/R)-induced myocardial injur...

Full description

Bibliographic Details
Main Authors: Bo Hu, Guangtao Xu, Yongxia Zheng, Fei Tong, Ping Qian, Xiaoyan Pan, Xinmei Zhou, Ruilin Shen
Format: Article
Language:English
Published: Karger Publishers 2017-06-01
Series:Kidney & Blood Pressure Research
Subjects:
Chelerythrine
Ischemia/reperfusion
Diabetes mellitus
Cystathionine-γ-lyase
Hydrogen disulfide
Protein kinase C
Nuclear factor-κ B
Online Access:http://www.karger.com/Article/FullText/477948

Internet

http://www.karger.com/Article/FullText/477948

Similar Items