The trace amine-associated receptor 1 modulates methamphetamine’s neurochemical and behavioural effects

The trace amine-associated receptor 1 modulates methamphetamine’s neurochemical and behavioural effects

The newly discovered trace amine-associated receptor 1 (TAAR1) has the ability to regulate both dopamine function and psychostimulant action. Here, we tested in rats the ability of RO5203648, a selective TAAR1 partial agonist, to modulate the physiological and behavioural effects of methamphetamine...

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Bibliographic Details
Main Authors: Rachel eCotter, Yue ePei, Liudmila eMus, Anja eHarmeier, Raul eGainetdinov, Marius Christian Hoener, Juan J Canales
Format: Article
Language:English
Published: Frontiers Media S.A. 2015-02-01
Series:Frontiers in Neuroscience
Subjects:
Methamphetamine
Microdialysis
Synaptosomes
self-administration
sensitization
trace amine-associated receptor
Online Access:http://journal.frontiersin.org/Journal/10.3389/fnins.2015.00039/full

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