Assisted reproductive technologies are associated with limited epigenetic variation at birth that largely resolves by adulthood

Use of Assisted Reproductive Technologies (ART) is increasing globally but their impact on long term health remains unclear. Here the authors show that ART-conceived individuals show variation in epigenetic profile at birth that largely resolves by adulthood, with no evidence of an impact on long te...

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Bibliographic Details
Main Authors: Boris Novakovic, Sharon Lewis, Jane Halliday, Joanne Kennedy, David P. Burgner, Anna Czajko, Bowon Kim, Alexandra Sexton-Oates, Markus Juonala, Karin Hammarberg, David J. Amor, Lex W. Doyle, Sarath Ranganathan, Liam Welsh, Michael Cheung, John McBain, Robert McLachlan, Richard Saffery
Format: Article
Language:English
Published: Nature Publishing Group 2019-09-01
Series:Nature Communications
Online Access:https://doi.org/10.1038/s41467-019-11929-9
Description
Summary:Use of Assisted Reproductive Technologies (ART) is increasing globally but their impact on long term health remains unclear. Here the authors show that ART-conceived individuals show variation in epigenetic profile at birth that largely resolves by adulthood, with no evidence of an impact on long term outcomes.
ISSN:2041-1723