RNA editing in cancer impacts mRNA abundance in immune response pathways

Abstract Background RNA editing generates modifications to the RNA sequences, thereby increasing protein diversity and shaping various layers of gene regulation. Recent studies have revealed global shifts in editing levels across many cancer types, as well as a few specific mechanisms implicating in...

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Bibliographic Details
Main Authors: Tracey W. Chan, Ting Fu, Jae Hoon Bahn, Hyun-Ik Jun, Jae-Hyung Lee, Giovanni Quinones-Valdez, Chonghui Cheng, Xinshu Xiao
Format: Article
Language:English
Published: BMC 2020-10-01
Series:Genome Biology
Online Access:http://link.springer.com/article/10.1186/s13059-020-02171-4