RNA editing in cancer impacts mRNA abundance in immune response pathways
Abstract Background RNA editing generates modifications to the RNA sequences, thereby increasing protein diversity and shaping various layers of gene regulation. Recent studies have revealed global shifts in editing levels across many cancer types, as well as a few specific mechanisms implicating in...
Main Authors: | , , , , , , , |
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Format: | Article |
Language: | English |
Published: |
BMC
2020-10-01
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Series: | Genome Biology |
Online Access: | http://link.springer.com/article/10.1186/s13059-020-02171-4 |