The HOTAIR/miR-214/ST6GAL1 crosstalk modulates colorectal cancer procession through mediating sialylated c-Met via JAK2/STAT3 cascade

Abstract Background The regulatory non-coding RNAs, including long non-coding RNAs (lncRNAs) and microRNAs (miRNAs), emerge as pivotal markers during tumor progression. Abnormal sialylated glycoprotein often leads to the malignancy of colorectal cancer (CRC). Methods Differential levels of HOTAIR an...

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Bibliographic Details
Main Authors: Bing Liu, Qianqian Liu, Shimeng Pan, Yiran Huang, Yu Qi, Shuangda Li, Yang Xiao, Li Jia
Format: Article
Language:English
Published: BMC 2019-11-01
Series:Journal of Experimental & Clinical Cancer Research
Subjects:
Online Access:http://link.springer.com/article/10.1186/s13046-019-1468-5