Etiological structure and clinical manifestations of influenza in Khanty-Mansiysk autonomous District-Ugra

• Main Authors: T. N. Ugleva, V. A. Pahotina
• Format: Article
• Language: Russian
• Published: Journal Infectology 2018-07-01
• Series: Žurnal Infektologii
• Subjects: influenza a; influenza b; the incidence of clinical manifestations; treatment
• Online Access: https://journal.niidi.ru/jofin/article/view/728

The aim of the study was to examine the incidence of influenza in  epidemic seasons from 2000 to 2017 in Khanty-Mansi Autonomous  Okrug — Yugra, analysis of selected pathogens flu, clinical course,  outcomes, risk and contingent. Used by the Russian Agency  management database Khanty-Mansijsky autonomous region-Yugra  weekly influenza morbidity, hospitalization, deaths, results of  antigenic analysis of selected influenza viruses (1203 biosample)  various age groups of the population from 22-x administrative  territories district. Clinical-Laboratory conducted a survey of 133  hospitalized patients, of whom 70 patients over 18 years and 63  child aged 7 months to 9 years. Results: when analyzing the highest  rates of flu were reported in the period 2000-2007, with a significant reduction in the beyond. The incidence of flu is caused by  a prior distribution of influenza A (H1N1-pdm), seasonal influenza A  (H1N1) and influenza A (H3N2). Epidemic season 2016/17, due to  the simultaneous circulation of influenza A virus (N3N2) (52.1%),  influenza A (H1N1) (39.6%) and influenza virus B (8.3%), was the  longest. High proportion of flu registered among children under 6  years (79%), as well as in non-immunized population (95%).  Compared with adults, children with influenza A (H1N1-pdm) is  characteristic fever lasting more than 3 febrile-x days (100%), a  combination of intoxic index with qatar syndrome of the upper  respiratory tract, 2 times more likely to develop viral and bacterial  pneumonia (23.8%). See influenza antiviral therapy high efficiency drug oseltamivir (Tamiflu) in children and adults.