Molecular Characterization of Astrocytoma Progression Towards Secondary Glioblastomas Utilizing Patient-Matched Tumor Pairs

Molecular Characterization of Astrocytoma Progression Towards Secondary Glioblastomas Utilizing Patient-Matched Tumor Pairs

Astrocytomas are primary human brain tumors including diffuse or anaplastic astrocytomas that develop towards secondary glioblastomas over time. However, only little is known about molecular alterations that drive this progression. We measured multi-omics profiles of patient-matched astrocytoma pair...

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Bibliographic Details
Main Authors: Michael Seifert, Gabriele Schackert, Achim Temme, Evelin Schröck, Andreas Deutsch, Barbara Klink
Format: Article
Language:English
Published: MDPI AG 2020-06-01
Series:Cancers
Subjects:
astrocytomas
patient-matched astrocytoma pairs
stage-wise astrocytoma development
secondary glioblastoma
cancer genomics
Online Access:https://www.mdpi.com/2072-6694/12/6/1696

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https://www.mdpi.com/2072-6694/12/6/1696

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