Carriers of the TCF7L2 rs7903146, rs12255372 risk alleles in the south Tamil Nadu T2DM patients present with early incidence and insulin dependence

Background and Aims: Metabolic abnormalities in T2DM (Type 2 diabetes mellitus) include classic manifestations such as impaired insulin secretion, synthesis and peripheral insulin resistance. The intronic variants rs7903146 and rs12255372 of the TCF7L2 (transcription factor 7-like 2) gene are strong...

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Bibliographic Details
Main Authors: Kumaravel Velayutham, Balaji Ramanathan, Jeyasudha Murugan, Arulvani Murugan, Vishali Thavamani, Rohini Gomathinayagam
Format: Article
Language:English
Published: Wolters Kluwer Medknow Publications 2019-01-01
Series:Indian Journal of Endocrinology and Metabolism
Subjects:
Online Access:http://www.ijem.in/article.asp?issn=2230-8210;year=2019;volume=23;issue=5;spage=563;epage=569;aulast=Velayutham