Importance of correlation between gene expression levels: application to the type I interferon signature in rheumatoid arthritis.

BACKGROUND: The analysis of gene expression data shows that many genes display similarity in their expression profiles suggesting some co-regulation. Here, we investigated the co-expression patterns in gene expression data and proposed a correlation-based research method to stratify individuals. MET...

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Bibliographic Details
Main Authors: Frédéric Reynier, Fabien Petit, Malick Paye, Fanny Turrel-Davin, Pierre-Emmanuel Imbert, Arnaud Hot, Bruno Mougin, Pierre Miossec
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2011-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3197194?pdf=render