Conditional Epistatic Interaction Maps Reveal Global Functional Rewiring of Genome Integrity Pathways in Escherichia coli

Conditional Epistatic Interaction Maps Reveal Global Functional Rewiring of Genome Integrity Pathways in Escherichia coli

As antibiotic resistance is increasingly becoming a public health concern, an improved understanding of the bacterial DNA damage response (DDR), which is commonly targeted by antibiotics, could be of tremendous therapeutic value. Although the genetic components of the bacterial DDR have been studied...

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Bibliographic Details
Main Authors: Ashwani Kumar, Natalia Beloglazova, Cedoljub Bundalovic-Torma, Sadhna Phanse, Viktor Deineko, Alla Gagarinova, Gabriel Musso, James Vlasblom, Sofia Lemak, Mohsen Hooshyar, Zoran Minic, Omar Wagih, Roberto Mosca, Patrick Aloy, Ashkan Golshani, John Parkinson, Andrew Emili, Alexander F. Yakunin, Mohan Babu
Format: Article
Language:English
Published: Elsevier 2016-01-01
Series:Cell Reports
Online Access:http://www.sciencedirect.com/science/article/pii/S2211124715015016

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