The Association of Tetrameric Acetylcholinesterase with ColQ Tail: A Block Normal Mode Analysis.
Acetylcholinesterase (AChE) rapidly hydrolyzes acetylcholine in the neuromuscular junctions and other cholinergic synapses to terminate the neuronal signal. In physiological conditions, AChE exists as tetramers associated with the proline-rich attachment domain (PRAD) of either collagen-like Q subun...
| Format: | Article |
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| Language: | English |
| Published: |
Public Library of Science (PLoS)
2005-11-01
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| Series: | PLoS Computational Biology |
| Online Access: | http://dx.doi.org/10.1371/journal.pcbi.0010062 |