Intracerebral administration of recombinant rabies virus expressing GM-CSF prevents the development of rabies after infection with street virus.

Intracerebral administration of recombinant rabies virus expressing GM-CSF prevents the development of rabies after infection with street virus.

Recently it was found that prior immunization with recombinant rabies virus (RABV) expressing granulocyte-macrophage colony-stimulating factor (GM-CSF) (LBNSE-GM-CSF) resulted in high innate/adaptive immune responses and protection against challenge with virulent RABV (Wen et al., JVI, 2011). In thi...

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Bibliographic Details
Main Authors: Hualei Wang, Guoqing Zhang, Yongjun Wen, Songtao Yang, Xianzhu Xia, Zhen F Fu
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2011-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3182207?pdf=render

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