BDNF mediates improvements in executive function following a 1-year exercise intervention

Executive function declines with age, but engaging in aerobic exercise may attenuate decline. One mechanism by which aerobic exercise may preserve executive function is through the up-regulation of brain-derived neurotropic factor (BDNF), which also declines with age. The present study examined BDNF...

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Main Authors: Regina Lynn Leckie, Lauren E Oberlin, Michelle W Voss, Ruchika S Prakash, Amanda eSzabo-Reed, Laura eChaddock-Heyman, Siobhan M Phillips, Neha P Gothe, Emily eMailey, Victoria Jeanne Vieira-Potter, Stephen A Martin, Brandt D Pence, Mingkuan eLin, Raja eParasuraman, Pamela M Greenwood, Karl J Fryxell, Jeffrey eWoods, Edward eMcAuley, Arthur F Kramer, Kirk I Erickson
Format: Article
Language:English
Published: Frontiers Media S.A. 2014-12-01
Series:Frontiers in Human Neuroscience
Subjects:
Online Access:http://journal.frontiersin.org/Journal/10.3389/fnhum.2014.00985/full