Salmonella modulates B cell biology to evade CD8+ T cell-mediated immune responses

Salmonella modulates B cell biology to evade CD8+ T cell-mediated immune responses

Although B cells and antibodies are the central effectors of humoral immunity, B cells can also produce and secrete cytokines and present antigen to helper T cells. The uptake of antigen is mainly mediated by endocytosis; thus, antigens are often presented by MHC-II molecules. However, it is unclea...

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Bibliographic Details
Main Authors: Marcela eLopez-Medina, Araceli ePerez-Lopez, Celia eAlpuche-Aranda, Vianney eOrtiz-Navarrete
Format: Article
Language:English
Published: Frontiers Media S.A. 2014-11-01
Series:Frontiers in Immunology
Subjects:
Salmonella
B cells
CD8 T cells
cross-presentation
PD-L1
Online Access:http://journal.frontiersin.org/Journal/10.3389/fimmu.2014.00586/full

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