Extracellular Vesicles as Mediators of Cellular Crosstalk Between Immune System and Kidney Graft

Extracellular Vesicles as Mediators of Cellular Crosstalk Between Immune System and Kidney Graft

Extracellular vesicles (EVs) are known immune-modulators exerting a critical role in kidney transplantation (KT). EV bioactive cargo includes graft antigens, costimulatory/inhibitory molecules, cytokines, growth factors, and functional microRNAs (miRNAs) that may modulate expression of recipient cel...

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Bibliographic Details
Main Authors: Marco Quaglia, Sergio Dellepiane, Gabriele Guglielmetti, Guido Merlotti, Giuseppe Castellano, Vincenzo Cantaluppi
Format: Article
Language:English
Published: Frontiers Media S.A. 2020-02-01
Series:Frontiers in Immunology
Subjects:
extracellular vesicles
acute rejection
ischemia-reperfusion syndrome
autoimmunity
renal transplant
biomarker
Online Access:https://www.frontiersin.org/article/10.3389/fimmu.2020.00074/full

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