Pharmacodynamic equivalence study of two preparations of eye drops, containing dorzolamide in healthy volunteers

Pharmacodynamic equivalence study of two preparations of eye drops, containing dorzolamide in healthy volunteers

Introduction: Dorzolamide 20mg/ml eye drops (dorzolamide hydrochloride (CAS: 120279-96-1)) is a topical carbonic anhydrase inhibitor indicated for the reduction of elevated intraocular pressure (IOP) in patients with open-angle glaucoma or ocular hypertension. The aim: The aim of the present study w...

Full description

Bibliographic Details
Main Authors:	Gatchev Emil M., Petrov Andrey D., Hristova Russka W., Demircheva Irenna S., Thyroff-Friesinger Ursula, Richter Wolfram H., Koytchev Rossen K.
Format:	Article
Language:	English
Published:	Srpsko lekarsko drustvo 2016-01-01
Series:	Hospital Pharmacology
Subjects:	dorzolamide eye drops intraocular pressure
Online Access:	http://scindeks-clanci.ceon.rs/data/pdf/2334-9492/2016/2334-94921602379G.pdf

Similar Items

Pharmacodynamic approach for proving equivalence of two ophtalmic solutions containing Brimonidine Tartarate 0.2% in healthy volunteers
by: Hristova-Valcheva Ruska, et al.
Published: (2018-01-01)

Effect of dorzolamide-timolol fixed combination prophylaxis on intraocular pressure spikes after intravitreal bevacizumab injection
by: Sehnaz Ozcaliskan, et al.
Published: (2015-06-01)

Comparison of brimonidine-timolol and dorzolamide-timolol in the management of intraocular pressure increase after phacoemulsiﬁcation
by: Adem Turk, et al.
Published: (2015-10-01)

Dramatic response to topical dorzolamide in X-linked retinoschisis
by: Rajeswari Thangavel, et al.
Published: (2020-01-01)

Juvenile X-Linked retinoschisis: Response to topical dorzolamide therapy
by: Krati Gupta, et al.
Published: (2018-01-01)

Efficacy of topical dorzolamide 2% in diabetic cystoid macular edema
by: Amani E Badawi, et al.
Published: (2021-09-01)

Effect of topical dorzolamide on rabbit central corneal thickness
by: Almeida Jr. G.C., et al.
Published: (2006-01-01)

Brinzolamide/timolol versus dorzolamide/timolol fixed combinations: A hospital-based, prospective, randomized study
by: Mary S Galose, et al.
Published: (2016-01-01)

Antioxidant activity of dorzolamide/timolol fixed combination in neuroprotective therapy in glaucoma
by: N. I. Kurysheva, et al.
Published: (2014-07-01)

Antioxidant activity of dorzolamide/timolol fixed combination in neuroprotective therapy in glaucoma
by: N. I. Kurysheva, et al.
Published: (2014-07-01)

Impact of dorzolamide, benzalkonium-preserved dorzolamide and benzalkonium-preserved brinzolamide on selected biomarkers of oxidative stress in the tear film
by: Lech Sedlak, et al.
Published: (2021-09-01)

Terapia combinada con timolol/dorzolamida versus timolol/pilocarpina en el glaucoma primario de ángulo abierto Combined therapy with timolol and dorzolamide vs timolol and pilocarpine used in primary open-angle glaucoma
by: Frank García González, et al.
Published: (2006-06-01)

<a name="home"></a>Effect of topical dorzolamide on rabbit central corneal thickness
by: G.C. Almeida Jr., et al.
Published: (2006-02-01)

Pressão intra-ocular após capsulotomia posterior com laser de Neodymium Yag em olhos pré-tratados com dorzolamida
by: Antonieta Antunes Pereira Minelio, et al.

Ocular hypotensive effects of a Rho-associated protein kinase inhibitor in rabbits
by: Kamaruddin MI, et al.
Published: (2017-03-01)

Efeitos maleato de timolol 0.5% do cloridrato de dorzolamida 2%, e da associação de ambas na pressão intra-ocular Efficacy of timolol maleate 0.5% dorzolamide hydrochloride 2%, and the combination of both drugs on intraocular pressure
by: A.G. Borges, et al.
Published: (2007-06-01)

Effects of dorzolamide/timolol fixed combination on retrobulbar hemodynamics in pseudoexfoliative glaucoma
by: Mustafa Eliacik, et al.
Published: (2016-01-01)

Effects of Latanoprost 0.005%/Timolol Maleate 0.5% and Dorzolamide 2%/Timolol Maleate 0.5% Fixed Combinations on 24-hour Intraocular Pressure in Patients with Primary Open-Angle Glaucoma
by: Berna Yüce, et al.
Published: (2012-01-01)

Active Pharmacovigilance in Peruvian Population: Surveillance of a Timolol/Brimonidine/Dorzolamide Ophthalmic Fixed Combination
by: Contreras-Salinas H, et al.
Published: (2021-02-01)

Regression of taxane-related cystoid macular edema after topical dorzolamide treatment: two case reports
by: Mitsuru Otsubo, et al.
Published: (2021-07-01)

Comparison of the efficacy and safety of fixed combination travoprost/timolol and dorzolamide/timolol in patients with primary open-angle glaucoma and ocular hypertension
by: Babić Nikola, et al.
Published: (2013-01-01)

Perioperative Administration of Topical Dorzolamide Hydrochloride/Timolol Maleate Reduces Postoperative Ocular Hypertension in Dogs Undergoing Cataract Surgery
by: Matusow, Rachel Brodman
Published: (2016)

Dorzolamide in a management of cystoid macular edema in a patient with retinitis pigmentosa sine pigmento
by: Karadžić Jelena, et al.
Published: (2017-01-01)

Efficacy and tolerability of brinzolamide/brimonidine suspension and prostaglandin analogs in patients previously treated with dorzolamide/timolol solution and prostaglandin analogs
by: Lo JS, et al.
Published: (2016-03-01)

Aqueous humor flow rate in normal cats and the effect of topical 2% dorzolamide on aqueous humor flow and intraocular pressure
by: Crumley, William R.
Published: (2011)

A 4-year retrospective study of add-on therapy to the fixed combination of dorzolamide/timolol for the treatment of POAG
by: Curt Hartleben-Matkin, et al.
Published: (2014-04-01)

Design, formulation and evaluation of carboxy methyl tamarind based in situ gelling ophthalmic drug delivery system of dorzolamide hydrochloride
by: Fatima Sanjeri Dasankoppa, et al.
Published: (2016-01-01)

Dorzolamida en el tratamiento del edema quístico macular poscirugía de catarata
by: Elianne Perera Miniet, et al.

Impact of combination of local carbonic anhydrase inhibitors and beta-blockers on intraocular pressure, visual functions and eye hemodynamics in primary open-angle glaucoma
by: T. N. Malishevskaya, et al.
Published: (2021-06-01)

Intraocular pressure-lowering effects of commonly used fixed combination drugs with timolol in the management of primary open angle glaucoma
by: Murat Atabey Ozer, et al.
Published: (2014-10-01)

Retinoprotective Effects of PACAP Eye Drops in Microbead-Induced Glaucoma Model in Rats
by: Edina Szabo, et al.
Published: (2021-08-01)

Sustained ocular delivery of Dorzolamide-HCl via proniosomal gel formulation: in-vitro characterization, statistical optimization, and in-vivo pharmacodynamic evaluation in rabbits
by: Nagwa Hussein Fouda, et al.
Published: (2018-01-01)

Toxicity and Physiological Actions of Carbonic Anhydrase Inhibitors to Aedes aegypti and Drosophila melanogaster
by: Sheena A. M. Francis, et al.
Published: (2016-12-01)

Drop-on-Demand Inkjet Drop Formation and Deposition
by: Dong, Hongming
Published: (2006)

Fruit drop: I. Specific characteristics and varietal properties of fruit drop
by: J. Racskó, et al.
Published: (2006-04-01)

Sulphonamide inhibition studies of the β-carbonic anhydrase from the bacterial pathogen Clostridium perfringens
by: Daniela Vullo, et al.
Published: (2018-01-01)

Efficacy and safety of various brimonidine formulations in the treatment of glaucoma and ocular hypertension
by: A. V. Sidorova, et al.
Published: (2021-07-01)

Untersuchungen zum Einfluss verschiedener Dosierungsintervalle von Dorzolamid, Dorzolamid-Timolol und Latanoprost auf den Intraokulardruck normotensiver Hunde
by: Schönfelder, Ralph
Published: (2010)

Iris Claw versus Scleral Fixation Intraocular Lens Implantation during Pars Plana Vitrectomy
by: Fereydoun Farrahi, et al.
Published: (2012-01-01)

THE CONSONANT DROPS, ITS REASONS AND VARIETIES IN TURKISH
by: Nadir İLHAN
Published: (2009-10-01)