Prediction of Clearance of Monoclonal and Polyclonal Antibodies and Non-Antibody Proteins in Children: Application of Allometric Scaling

Allometric scaling can be used for the extrapolation of pharmacokinetic parameters from adults to children. The objective of this study was to predict clearance of therapeutic proteins (monoclonal and polyclonal antibodies and non-antibody proteins) allometrically in preterm neonates to adolescents....

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Bibliographic Details
Main Author: Iftekhar Mahmood
Format: Article
Language:English
Published: MDPI AG 2020-08-01
Series:Antibodies
Subjects:
Online Access:https://www.mdpi.com/2073-4468/9/3/40