Characteristics and Survival Rate of Patients with Gastric and Gastroesophageal Junction Adenocarcinoma in Yazd, Iran

• Main Authors: Ali Akhavan, Fariba Binesh, Azadeh Seifaddiny, Fazloallah Ghannadi
• Format: Article
• Language: English
• Published: Shiraz University of Medical Sciences 2013-07-01
• Series: Middle East Journal of Cancer
• Subjects: Stomach; Adenocarcinoma; Chemotherapy; Radiotherapy; Survival
• Online Access: http://mejc.sums.ac.ir/index.php/mejc/article/view/14/7

Background:Gastric cancer is the leading cause of cancer deaths in Iran. Treatmentfor gastric adenocarcinoma varies worldwide. The aim of this study is to evaluate char-acteristics and survival rate of gastric and gastroesophageal junction adenocarcinomain Yazd, Iran.Methods: This study was conducted on 53 patients with gastric or gastroesophagealjunction adenocarcioma who referred to Shahid Ramezanzadeh Radiation OncologyCenter between 2004 and 2010. All patients underwent surgery, chemotherapy andradiotherapy. Data from patients’ records were extracted and follow up was conductedthrough telephone contacts. To analyze data, Kaplan Meier curves and SPSS softwarewere employed.Results: There were 17 (32.1%) female and 36 (67.9%) male patients. The meanage was 58.32 years. CT scans were performed preoperatively for 18 (34%) patients.In 14 (26.9%) patients no lymph node was resected or reported by the pathologist; in29 (54.7%) patients one to six lymph nodes were found; and in 10 (18.9%) patientsseven lymph nodes or more were detected. In 2 (3.77%) patients there were more thanfifteen lymph nodes resected. Surgical staging was impossible for 16 (30.2%) patients.Mean survival was 50.9 months and median survival was 51 months. The survival rateswere 73% for three years, 36% for five years and 18% for seven years. Among thevariables only histologic grade had a significant relation to survival.Conclusion: Preoperative staging procedures and surgical resections are inadequatein our province. Survival rates are acceptable and similar to Western countries. Thisfinding may have been the result of the effectiveness of combination chemotherapyregimens and radiotherapy used in our patients.