Antibiotic and Antiinflammatory Therapy Transiently Reduces Inflammation and Hypercoagulation in Acutely SIV-Infected Pigtailed Macaques.

Antibiotic and Antiinflammatory Therapy Transiently Reduces Inflammation and Hypercoagulation in Acutely SIV-Infected Pigtailed Macaques.

Increased chronic immune activation and inflammation are hallmarks of HIV/SIV infection and are highly correlated with progression to AIDS and development of non-AIDS comorbidities, such as hypercoagulability and cardiovascular disease. Intestinal dysfunction resulting in microbial translocation has...

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Bibliographic Details
Main Authors:	Ivona Pandrea, Cuiling Xu, Jennifer L Stock, Daniel N Frank, Dongzhu Ma, Benjamin B Policicchio, Tianyu He, Jan Kristoff, Elaine Cornell, George S Haret-Richter, Anita Trichel, Ruy M Ribeiro, Russell Tracy, Cara Wilson, Alan L Landay, Cristian Apetrei
Format:	Article
Language:	English
Published:	Public Library of Science (PLoS) 2016-01-01
Series:	PLoS Pathogens
Online Access:	https://doi.org/10.1371/journal.ppat.1005384

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