Bacterial vaginosis and human immunodeficiency virus infection
<p>Abstract</p> <p>Epidemiologic studies indicate that bacterial vaginosis (BV), a common alteration of lower genital tract flora in women, is associated with increased susceptibility to HIV infection. Other recent studies show that HIV is detected more frequently and at higher lev...
| Main Authors: | , , |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
BMC
2007-10-01
|
| Series: | AIDS Research and Therapy |
| Online Access: | http://www.aidsrestherapy.com/content/4/1/25 |
| id |
doaj-9f846a81f3514be49202efbaa6d69e87 |
|---|---|
| record_format |
Article |
| spelling |
doaj-9f846a81f3514be49202efbaa6d69e872020-11-24T21:04:31ZengBMCAIDS Research and Therapy1742-64052007-10-01412510.1186/1742-6405-4-25Bacterial vaginosis and human immunodeficiency virus infectionZariffard M RezaSt John ElizabethSpear Gregory T<p>Abstract</p> <p>Epidemiologic studies indicate that bacterial vaginosis (BV), a common alteration of lower genital tract flora in women, is associated with increased susceptibility to HIV infection. Other recent studies show that HIV is detected more frequently and at higher levels in the lower genital tract of HIV-seropositive women with BV. In vitro studies show that genital tract secretions from women with BV or flora associated with BV induce HIV expression in infected cells. The increased HIV expression appears to be due at least in part to activation through Toll-like receptors (TLR), specifically TLR2. Further research is needed to elucidate how BV contributes to HIV acquisition and transmission.</p> http://www.aidsrestherapy.com/content/4/1/25 |
| collection |
DOAJ |
| language |
English |
| format |
Article |
| sources |
DOAJ |
| author |
Zariffard M Reza St John Elizabeth Spear Gregory T |
| spellingShingle |
Zariffard M Reza St John Elizabeth Spear Gregory T Bacterial vaginosis and human immunodeficiency virus infection AIDS Research and Therapy |
| author_facet |
Zariffard M Reza St John Elizabeth Spear Gregory T |
| author_sort |
Zariffard M Reza |
| title |
Bacterial vaginosis and human immunodeficiency virus infection |
| title_short |
Bacterial vaginosis and human immunodeficiency virus infection |
| title_full |
Bacterial vaginosis and human immunodeficiency virus infection |
| title_fullStr |
Bacterial vaginosis and human immunodeficiency virus infection |
| title_full_unstemmed |
Bacterial vaginosis and human immunodeficiency virus infection |
| title_sort |
bacterial vaginosis and human immunodeficiency virus infection |
| publisher |
BMC |
| series |
AIDS Research and Therapy |
| issn |
1742-6405 |
| publishDate |
2007-10-01 |
| description |
<p>Abstract</p> <p>Epidemiologic studies indicate that bacterial vaginosis (BV), a common alteration of lower genital tract flora in women, is associated with increased susceptibility to HIV infection. Other recent studies show that HIV is detected more frequently and at higher levels in the lower genital tract of HIV-seropositive women with BV. In vitro studies show that genital tract secretions from women with BV or flora associated with BV induce HIV expression in infected cells. The increased HIV expression appears to be due at least in part to activation through Toll-like receptors (TLR), specifically TLR2. Further research is needed to elucidate how BV contributes to HIV acquisition and transmission.</p> |
| url |
http://www.aidsrestherapy.com/content/4/1/25 |
| work_keys_str_mv |
AT zariffardmreza bacterialvaginosisandhumanimmunodeficiencyvirusinfection AT stjohnelizabeth bacterialvaginosisandhumanimmunodeficiencyvirusinfection AT speargregoryt bacterialvaginosisandhumanimmunodeficiencyvirusinfection |
| _version_ |
1716770804534870016 |