Coping with family structure in genome-wide association studies: a comparative evaluation

Abstract In this paper, a fully statistical investigation of the control of family structure as random effects is analyzed and discussed, using both the genome-wide association studies (GWAS) data and simulated data. Three modeling strategies are proposed and the analysis results suggest the hybrid...

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Bibliographic Details
Main Authors: Yayun Hsu, Jonathan Auerbach, Tian Zheng, Shaw-hwa Lo
Format: Article
Language:English
Published: BMC 2018-09-01
Series:BMC Proceedings
Online Access:http://link.springer.com/article/10.1186/s12919-018-0151-8

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