Hsa-miR-99b/let-7e/miR-125a Cluster Regulates Pathogen Recognition Receptor-Stimulated Suppressive Antigen-Presenting Cells

Hsa-miR-99b/let-7e/miR-125a Cluster Regulates Pathogen Recognition Receptor-Stimulated Suppressive Antigen-Presenting Cells

Antigen-presenting cells (APCs) regulate the balance of our immune response toward microbes. Whereas immunogenic APCs boost inflammation and activate lymphocytes, the highly plastic cells can switch into a tolerogenic/suppressive phenotype that dampens and resolves the response. Thereby the initiall...

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Bibliographic Details
Main Authors:	Dagmar Hildebrand, Mariel-Esther Eberle, Sabine Marie Wölfle, Franziska Egler, Delal Sahin, Aline Sähr, Konrad A. Bode, Klaus Heeg
Format:	Article
Language:	English
Published:	Frontiers Media S.A. 2018-06-01
Series:	Frontiers in Immunology
Subjects:	suppressive antigen-presenting cell miRNA hsa-miR-99b/let-7e/miR-125a cluster signal transducer and activator of transcription 3 programmed death-ligand 1 indolamin-2,3-dioxygenase
Online Access:	https://www.frontiersin.org/article/10.3389/fimmu.2018.01224/full

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